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Mps1 dimerization and multisite interactions with Ndc80 complex enable responsive spindle assembly checkpoint signaling
Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, which is monitored by the spindle assembly checkpoint (SAC) signaling. As an upstream factor of SAC, the precise and dynamic kinetochore localization of Mps1 kinase is critical for initiating and silencing SAC sign...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493027/ https://www.ncbi.nlm.nih.gov/pubmed/32219319 http://dx.doi.org/10.1093/jmcb/mjaa006 |