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An open label study of the safety and efficacy of a single dose of weekly chloroquine and azithromycin administered for malaria prophylaxis in healthy adults challenged with 7G8 chloroquine-resistant Plasmodium falciparum in a controlled human malaria infection model

BACKGROUND: Malaria remains the top infectious disease threat facing the U.S. military in many forward operating environments. Compliance with malaria chemoprophylaxis remains a critical component in preventing malaria in the deployed Service Member. Studies of previous military operations show that...

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Detalles Bibliográficos
Autores principales: Livezey, Jeffrey, Twomey, Patrick, Morrison, Meshell, Cicatelli, Susan, Duncan, Elizabeth H., Hamer, Melinda, Lee, Christine, Hutter, Jack, Mills, Kristin, DeLuca, Jesse, Poon, Lucas, Selig, Daniel, Vuong, Chau, Sousa, Jason, Oliver, Thomas, Bennett, Jason, Moon, James E., Sikaffy, April, Sedegah, Martha, Tosh, Donna, Kreishman-Deitrick, Mara, Waterman, Paige
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493140/
https://www.ncbi.nlm.nih.gov/pubmed/32938444
http://dx.doi.org/10.1186/s12936-020-03409-z