Heterologous redox partners supporting the efficient catalysis of epothilone B biosynthesis by EpoK in Schlegelella brevitalea

BACKGROUND: Epothilone B is a natural product that stabilizes microtubules, similar to paclitaxel (Taxol); therefore, epothilone B and several derivatives have shown obvious antitumour activities. Some of these products are in clinical trials, and one (ixabepilone, BMS) is already on the market, hav...

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Detalles Bibliográficos
Autores principales: Liang, Junheng, Wang, Huimin, Bian, Xiaoying, Zhang, Youming, Zhao, Guoping, Ding, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493146/
https://www.ncbi.nlm.nih.gov/pubmed/32933531
http://dx.doi.org/10.1186/s12934-020-01439-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493146/
https://www.ncbi.nlm.nih.gov/pubmed/32933531
http://dx.doi.org/10.1186/s12934-020-01439-5

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