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Pentraxin 3 promotes airway inflammation in experimental asthma

BACKGROUND: Pentraxin 3 (PTX3) regulates multiple aspects of innate immunity and tissue inflammation. Recently, it has been reported that PTX3 deficiency enhances interleukin (IL)-17A–dominant pulmonary inflammation in an ovalbumin (OVA)-induced mouse asthma model. However, whether PTX3 treatment wo...

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Detalles Bibliográficos
Autores principales: Gao, Pengfei, Tang, Kun, Lu, Yanjiao, Huang, Zhenli, Wang, Shanshan, Wang, Meijia, Wang, Jianmiao, Zhao, Jianping, Xie, Jungang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493172/
https://www.ncbi.nlm.nih.gov/pubmed/32938460
http://dx.doi.org/10.1186/s12931-020-01499-6