Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes

[Image: see text] We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac)(2) and (R)-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities.

Detalles Bibliográficos
Autores principales: Dian, Longyang, Marek, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493299/
https://www.ncbi.nlm.nih.gov/pubmed/32953232
http://dx.doi.org/10.1021/acscatal.9b04960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493299/
https://www.ncbi.nlm.nih.gov/pubmed/32953232
http://dx.doi.org/10.1021/acscatal.9b04960

Ejemplares similares