Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes

[Image: see text] We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac)(2) and (R)-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities.

Detalles Bibliográficos
Autores principales: Dian, Longyang, Marek, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493299/
https://www.ncbi.nlm.nih.gov/pubmed/32953232
http://dx.doi.org/10.1021/acscatal.9b04960
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author Dian, Longyang
Marek, Ilan
author_facet Dian, Longyang
Marek, Ilan
author_sort Dian, Longyang
collection PubMed
description [Image: see text] We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac)(2) and (R)-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities.
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spelling pubmed-74932992020-09-16 Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes Dian, Longyang Marek, Ilan ACS Catal [Image: see text] We report herein an easy, mild, and robust Pd-catalyzed enantioselective hydroalkynylation reaction of achiral cyclopropenes. Commercially available Pd(acac)(2) and (R)-DM-BINAP proved to be the best combination to reach high diastereo- and enantioselectivities. American Chemical Society 2019-12-26 2020-01-17 /pmc/articles/PMC7493299/ /pubmed/32953232 http://dx.doi.org/10.1021/acscatal.9b04960 Text en Copyright © 2019 American Chemical Society This is an open access article published under an ACS AuthorChoice License (http://pubs.acs.org/page/policy/authorchoice_termsofuse.html) , which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
spellingShingle Dian, Longyang
Marek, Ilan
Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes
title Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes
title_full Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes
title_fullStr Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes
title_full_unstemmed Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes
title_short Pd-Catalyzed Enantioselective Hydroalkynylation of Cyclopropenes
title_sort pd-catalyzed enantioselective hydroalkynylation of cyclopropenes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493299/
https://www.ncbi.nlm.nih.gov/pubmed/32953232
http://dx.doi.org/10.1021/acscatal.9b04960
work_keys_str_mv AT dianlongyang pdcatalyzedenantioselectivehydroalkynylationofcyclopropenes
AT marekilan pdcatalyzedenantioselectivehydroalkynylationofcyclopropenes

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