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IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent way

BACKGROUND: Insulin-like growth factor 2 (IGF2) messenger RNA binding protein 3 (IMP3) has been testified to be overexpressed in prostate cancer and strongly related to patients’ poor prognosis. However, the functions of IMP3 and the underlying mechanisms in prostate cancer still remain unknown. The...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang, Wang, Dawei, Liu, Boke, Jin, Xingwei, Wang, Xianjin, Pan, Junwei, Tu, Weichao, Shao, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493339/
https://www.ncbi.nlm.nih.gov/pubmed/32938489
http://dx.doi.org/10.1186/s13046-020-01657-0