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Single oral fixed-dose praziquantel-miltefosine nanocombination for effective control of experimental schistosomiasis mansoni

BACKGROUND: The control of schistosomiasis has been centered to date on a single drug, praziquantel, with shortcomings including treatment failure, reinfection, and emergence of drug resistance. Drug repurposing, combination therapy or nanotechnology were explored to improve antischistosomal treatme...

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Detalles Bibliográficos
Autores principales: Eissa, Maha M., El-Azzouni, Mervat Z., El-Khordagui, Labiba K., Abdel Bary, Amany, El-Moslemany, Riham M., Abdel Salam, Sara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493353/
https://www.ncbi.nlm.nih.gov/pubmed/32933556
http://dx.doi.org/10.1186/s13071-020-04346-1