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MEIRLOP: improving score-based motif enrichment by incorporating sequence bias covariates

BACKGROUND: Motif enrichment analysis (MEA) identifies over-represented transcription factor binding (TF) motifs in the DNA sequence of regulatory regions, enabling researchers to infer which transcription factors can regulate transcriptional response to a stimulus, or identify sequence features fou...

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Detalles Bibliográficos
Autores principales: Delos Santos, Nathaniel P., Texari, Lorane, Benner, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493370/
https://www.ncbi.nlm.nih.gov/pubmed/32938397
http://dx.doi.org/10.1186/s12859-020-03739-4