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MEIRLOP: improving score-based motif enrichment by incorporating sequence bias covariates
BACKGROUND: Motif enrichment analysis (MEA) identifies over-represented transcription factor binding (TF) motifs in the DNA sequence of regulatory regions, enabling researchers to infer which transcription factors can regulate transcriptional response to a stimulus, or identify sequence features fou...
Autores principales: | Delos Santos, Nathaniel P., Texari, Lorane, Benner, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493370/ https://www.ncbi.nlm.nih.gov/pubmed/32938397 http://dx.doi.org/10.1186/s12859-020-03739-4 |
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