Targeting Follistatin like 1 ameliorates liver fibrosis induced by carbon tetrachloride through TGF-β1-miR29a in mice

BACKGROUND: Hepatic fibrosis is a pathological response of the liver to a variety of chronic stimuli. Hepatic stellate cells (HSCs) are the major source of myofibroblasts in the liver. Follistatin like 1 (Fstl1) is a secreted glycoprotein induced by transforming growth factor-β1 (TGF-β1). However, t...

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Detalles Bibliográficos
Autores principales: Xu, Xin-Yi, Du, Yan, Liu, Xue, Ren, Yilin, Dong, Yingying, Xu, Hong-Yu, Shi, Jin-Song, Jiang, Dianhua, Xu, Xin, Li, Lian, Xu, Zheng-Hong, Geng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493388/
https://www.ncbi.nlm.nih.gov/pubmed/32933544
http://dx.doi.org/10.1186/s12964-020-00610-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493388/
https://www.ncbi.nlm.nih.gov/pubmed/32933544
http://dx.doi.org/10.1186/s12964-020-00610-0

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