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Detection of mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains inhibiting wild type probe hybridization in the MTBDR plus assay by DNA sequencing directly from clinical specimens

BACKGROUND: The potential of genetic testing for rapid and accurate diagnosis of drug-resistant Mycobacterium tuberculosis strains is vital for efficient treatment and reduction in dissemination. MTBDR plus assays rapidly detect mutations related to drug resistance and wild type sequences allied wit...

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Detalles Bibliográficos
Autores principales: Sinha, Pallavi, Srivastava, G. N., Tripathi, Rajneesh, Mishra, Mukti Nath, Anupurba, Shampa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493411/
https://www.ncbi.nlm.nih.gov/pubmed/32938393
http://dx.doi.org/10.1186/s12866-020-01967-5