Cargando…
Detection of mutations in the rpoB gene of rifampicin-resistant Mycobacterium tuberculosis strains inhibiting wild type probe hybridization in the MTBDR plus assay by DNA sequencing directly from clinical specimens
BACKGROUND: The potential of genetic testing for rapid and accurate diagnosis of drug-resistant Mycobacterium tuberculosis strains is vital for efficient treatment and reduction in dissemination. MTBDR plus assays rapidly detect mutations related to drug resistance and wild type sequences allied wit...
Autores principales: | Sinha, Pallavi, Srivastava, G. N., Tripathi, Rajneesh, Mishra, Mukti Nath, Anupurba, Shampa |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493411/ https://www.ncbi.nlm.nih.gov/pubmed/32938393 http://dx.doi.org/10.1186/s12866-020-01967-5 |
Ejemplares similares
-
Detection of Beijing strains of MDR M. tuberculosis and their association with drug resistance mutations in katG, rpoB, and embB genes
por: Gupta, Anamika, et al.
Publicado: (2020) -
HIV Coinfection Is Associated with Low-Fitness rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis
por: Loiseau, Chloé, et al.
Publicado: (2020) -
A Glutamine Insertion at Codon 432 of RpoB Confers Rifampicin Resistance in Mycobacterium tuberculosis
por: Lai, Li-Yin, et al.
Publicado: (2020) -
The Structural Basis of Mycobacterium tuberculosis RpoB Drug-Resistant Clinical Mutations on Rifampicin Drug Binding
por: Amusengeri, Arnold, et al.
Publicado: (2022) -
Rapid detection of drug-resistant Mycobacterium tuberculosis directly from clinical specimens using allele-specific polymerase chain reaction assay
por: Sinha, Pallavi, et al.
Publicado: (2019)