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Transplantation of a Novel Recombinant Adeno-Associated Virus (pAAV-HE1B19K-TE1A) Demonstrates Higher Anti-Tumor Effects in Tumor Cells

BACKGROUND: Oncolytic viruses (OVs) can specifically infect and kill tumor cells. Adeno-associated virus (AAV) is a widely-studied OV. This study aimed to construct a tumor-targeted recombinant AAV using genetic engineering technology. MATERIAL/METHODS: The transgene plasmid pAAV-HE1B19K-TE1A was co...

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Detalles Bibliográficos
Autores principales: Li, Zhuo-Qing, Shen, Hong, Shu, Kun-Xian, Li, Jian-Jun, Tang, Yin, Su, Jing-Jing, Yan, Jun, Yang, Jie, Wang, Ze-Qing, Qiu, Yan, Yang, Yong, Liu, Yang, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493455/
https://www.ncbi.nlm.nih.gov/pubmed/32883945
http://dx.doi.org/10.12659/AOT.925013