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Association Between a Variable Number Tandem Repeat Polymorphism Within the DAT1 Gene and the Mesolimbic Pathway in Parkinson's Disease

The loss of ventral striatal dopaminergic neurons in Parkinson's disease (PD) predicts an impact on the reward system. The ventrostriatal system is involved in motivational processing and its dysfunction may be related to non-motor symptoms such as depression and apathy. We previously documente...

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Detalles Bibliográficos
Autores principales: du Plessis, Stefan, Bekker, Minke, Buckle, Chanelle, Vink, Matthijs, Seedat, Soraya, Bardien, Soraya, Carr, Jonathan, Abrahams, Shameemah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493621/
https://www.ncbi.nlm.nih.gov/pubmed/32982958
http://dx.doi.org/10.3389/fneur.2020.00982