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Association Between a Variable Number Tandem Repeat Polymorphism Within the DAT1 Gene and the Mesolimbic Pathway in Parkinson's Disease
The loss of ventral striatal dopaminergic neurons in Parkinson's disease (PD) predicts an impact on the reward system. The ventrostriatal system is involved in motivational processing and its dysfunction may be related to non-motor symptoms such as depression and apathy. We previously documente...
Autores principales: | du Plessis, Stefan, Bekker, Minke, Buckle, Chanelle, Vink, Matthijs, Seedat, Soraya, Bardien, Soraya, Carr, Jonathan, Abrahams, Shameemah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493621/ https://www.ncbi.nlm.nih.gov/pubmed/32982958 http://dx.doi.org/10.3389/fneur.2020.00982 |
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