CA IX Stabilizes Intracellular pH to Maintain Metabolic Reprogramming and Proliferation in Hypoxia

Tumor hypoxia represents a severe microenvironmental stress that is frequently associated with acidosis. Cancer cells respond to these stresses with changes in gene expression that promote survival at least in part through pH regulation and metabolic reprogramming. Hypoxia-induced carbonic anhydrase...

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Detalles Bibliográficos
Autores principales: Benej, Martin, Svastova, Eliska, Banova, Radivojka, Kopacek, Juraj, Gibadulinova, Adriana, Kery, Martin, Arena, Simona, Scaloni, Andrea, Vitale, Monica, Zambrano, Nicola, Papandreou, Ioanna, Denko, Nicholas C., Pastorekova, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493625/
https://www.ncbi.nlm.nih.gov/pubmed/32983978
http://dx.doi.org/10.3389/fonc.2020.01462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493625/
https://www.ncbi.nlm.nih.gov/pubmed/32983978
http://dx.doi.org/10.3389/fonc.2020.01462

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