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Taming the cytokine storm: repurposing montelukast for the attenuation and prophylaxis of severe COVID-19 symptoms

As a result of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, a clinical complication can arise that is characterized by a hyperinflammatory cytokine profile, often termed a ‘cytokine storm’. A protein complex (nuclear factor kappa-light-chain-enhancer of activated B cells;...

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Detalles Bibliográficos
Autores principales: Sanghai, Nitesh, Tranmer, Geoffrey K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493735/
https://www.ncbi.nlm.nih.gov/pubmed/32949526
http://dx.doi.org/10.1016/j.drudis.2020.09.013