PertInInt: An Integrative, Analytical Approach to Rapidly Uncover Cancer Driver Genes with Perturbed Interactions and Functionalities

A major challenge in cancer genomics is to identify genes with functional roles in cancer and uncover their mechanisms of action. We introduce an integrative framework that identifies cancer-relevant genes by pinpointing those whose interaction or other functional sites are enriched in somatic mutat...

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Detalles Bibliográficos
Autores principales: Kobren, Shilpa Nadimpalli, Chazelle, Bernard, Singh, Mona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493809/
https://www.ncbi.nlm.nih.gov/pubmed/32711844
http://dx.doi.org/10.1016/j.cels.2020.06.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493809/
https://www.ncbi.nlm.nih.gov/pubmed/32711844
http://dx.doi.org/10.1016/j.cels.2020.06.005

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