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Poly(ADP-ribose) Polymerase 1 (PARP1) restrains MyoD-dependent gene expression during muscle differentiation

The myogenic factor MyoD regulates skeletal muscle differentiation by interacting with a variety of chromatin-modifying complexes. Although MyoD can induce and maintain chromatin accessibility at its target genes, its binding and trans-activation ability can be limited by some types of not fully cha...

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Detalles Bibliográficos
Autores principales: Matteini, Francesca, Andresini, Oriella, Petrai, Stefano, Battistelli, Cecilia, Rossi, Marianna Nicoletta, Maione, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493885/
https://www.ncbi.nlm.nih.gov/pubmed/32934320
http://dx.doi.org/10.1038/s41598-020-72155-8