Cargando…

The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer

The execution phase of apoptosis is a critical process in programmed cell death in response to a multitude of cellular stresses. A crucial component of this pathway is the apoptosome, a platform for the activation of pro-caspase 9 (PC9). Recent findings have shown that autocleavage of PC9 to Caspase...

Descripción completa

Detalles Bibliográficos
Autores principales: Fullstone, Gavin, Bauer, Tabea L., Guttà, Cristiano, Salvucci, Manuela, Prehn, Jochen H. M., Rehm, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493894/
https://www.ncbi.nlm.nih.gov/pubmed/32341447
http://dx.doi.org/10.1038/s41418-020-0545-9