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The apoptosome molecular timer synergises with XIAP to suppress apoptosis execution and contributes to prognosticating survival in colorectal cancer
The execution phase of apoptosis is a critical process in programmed cell death in response to a multitude of cellular stresses. A crucial component of this pathway is the apoptosome, a platform for the activation of pro-caspase 9 (PC9). Recent findings have shown that autocleavage of PC9 to Caspase...
Autores principales: | Fullstone, Gavin, Bauer, Tabea L., Guttà, Cristiano, Salvucci, Manuela, Prehn, Jochen H. M., Rehm, Markus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493894/ https://www.ncbi.nlm.nih.gov/pubmed/32341447 http://dx.doi.org/10.1038/s41418-020-0545-9 |
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