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Gremlin-1 augments the oestrogen-related receptor α signalling through EGFR activation: implications for the progression of breast cancer

BACKGROUND: Gremlin-1 (GREM1), one of the bone morphogenetic protein antagonists, is involved in organogenesis, tissue differentiation and kidney development. However, the role of GREM1 in cancer progression and its underlying mechanisms remain poorly understood. METHODS: The role of GREM1 in breast...

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Detalles Bibliográficos
Autores principales: Park, Sin-Aye, Sung, Nam Ji, Choi, Bae-Jung, Kim, Wonki, Kim, Seung Hyeon, Surh, Young-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493948/
https://www.ncbi.nlm.nih.gov/pubmed/32572171
http://dx.doi.org/10.1038/s41416-020-0945-0