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Gremlin-1 augments the oestrogen-related receptor α signalling through EGFR activation: implications for the progression of breast cancer
BACKGROUND: Gremlin-1 (GREM1), one of the bone morphogenetic protein antagonists, is involved in organogenesis, tissue differentiation and kidney development. However, the role of GREM1 in cancer progression and its underlying mechanisms remain poorly understood. METHODS: The role of GREM1 in breast...
Autores principales: | Park, Sin-Aye, Sung, Nam Ji, Choi, Bae-Jung, Kim, Wonki, Kim, Seung Hyeon, Surh, Young-Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493948/ https://www.ncbi.nlm.nih.gov/pubmed/32572171 http://dx.doi.org/10.1038/s41416-020-0945-0 |
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