EZH2 reduction is an essential mechanoresponse for the maintenance of super-enhancer polarization against compressive stress in human periodontal ligament stem cells

Despite the ubiquitous mechanical cues at both spatial and temporal dimensions, cell identities and functions are largely immune to the everchanging mechanical stimuli. To understand the molecular basis of this epigenetic stability, we interrogated compressive force-elicited transcriptomic changes i...

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Detalles Bibliográficos
Autores principales: Li, Qian, Sun, Xiwen, Tang, Yunyi, Qu, Yanan, Zhou, Yanheng, Zhang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493952/
https://www.ncbi.nlm.nih.gov/pubmed/32934212
http://dx.doi.org/10.1038/s41419-020-02963-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493952/
https://www.ncbi.nlm.nih.gov/pubmed/32934212
http://dx.doi.org/10.1038/s41419-020-02963-3

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