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TET2 directs mammary luminal cell differentiation and endocrine response

Epigenetic regulation plays an important role in governing stem cell fate and tumorigenesis. Lost expression of a key DNA demethylation enzyme TET2 is associated with human cancers and has been linked to stem cell traits in vitro; however, whether and how TET2 regulates mammary stem cell fate and ma...

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Detalles Bibliográficos
Autores principales: Kim, Mi Ran, Wu, Meng-Ju, Zhang, Yingsheng, Yang, Jer-Yen, Chang, Chun Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7493981/
https://www.ncbi.nlm.nih.gov/pubmed/32934200
http://dx.doi.org/10.1038/s41467-020-18129-w