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Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling
The small GTPase RhoA is a central signaling enzyme that is involved in various cellular processes such as cytoskeletal dynamics, transcription, and cell cycle progression. Many signal transduction pathways activate RhoA—for instance, Gα(q)-coupled Histamine 1 Receptor signaling via Gα(q)-dependent...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494096/ https://www.ncbi.nlm.nih.gov/pubmed/32881857 http://dx.doi.org/10.1371/journal.pbio.3000866 |