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Apoptosis in idiopathic inflammatory myopathies with partial invasion; a role for CD8(+) cytotoxic T cells?

Polymyositis and inclusion body myositis are idiopathic inflammatory myopathies, with a pathology characterized by partial invasion of non-necrotic muscle fibres by CD8(+) cytotoxic T-cells, leading to fibre degeneration. Although the main effector pathway of CD8(+) T-cells is to induce apoptosis of...

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Detalles Bibliográficos
Autores principales: Danielsson, Olof, Häggqvist, Bo, Gröntoft, Liv, Öllinger, Karin, Ernerudh, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494097/
https://www.ncbi.nlm.nih.gov/pubmed/32936839
http://dx.doi.org/10.1371/journal.pone.0239176