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Telacebec (Q203)-containing intermittent oral regimens sterilized mice infected with Mycobacterium ulcerans after only 16 doses

Buruli ulcer (BU), caused by Mycobacterium ulcerans, is currently treated with a daily combination of rifampin and either injectable streptomycin or oral clarithromycin. An intermittent oral regimen would facilitate treatment supervision. We first evaluated the bactericidal activity of newer antimic...

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Detalles Bibliográficos
Autores principales: Chauffour, Aurélie, Robert, Jérôme, Veziris, Nicolas, Aubry, Alexandra, Pethe, Kevin, Jarlier, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494103/
https://www.ncbi.nlm.nih.gov/pubmed/32866170
http://dx.doi.org/10.1371/journal.pntd.0007857