A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells

How time is measured by neural stem cells during temporal neurogenesis has remained unresolved. By combining experiments and computational modeling, we define a Shh/Gli-driven three-node timer underlying the sequential generation of motor neurons (MNs) and serotonergic neurons in the brainstem. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Dias, José M., Alekseenko, Zhanna, Jeggari, Ashwini, Boareto, Marcelo, Vollmer, Jannik, Kozhevnikova, Mariya, Wang, Hui, Matise, Michael P., Alexeyenko, Andrey, Iber, Dagmar, Ericson, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494341/
https://www.ncbi.nlm.nih.gov/pubmed/32938678
http://dx.doi.org/10.1126/sciadv.aba8196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494341/
https://www.ncbi.nlm.nih.gov/pubmed/32938678
http://dx.doi.org/10.1126/sciadv.aba8196

Ejemplares similares