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Atomic-scale characterization of mature HIV-1 capsid stabilization by inositol hexakisphosphate (IP(6))
Inositol hexakisphosphates (IP(6)) are cellular cofactors that promote the assembly of mature capsids of HIV. These negatively charged molecules coordinate an electropositive ring of arginines at the center of pores distributed throughout the capsid surface. Kinetic studies indicate that the binding...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494349/ https://www.ncbi.nlm.nih.gov/pubmed/32938668 http://dx.doi.org/10.1126/sciadv.abc6465 |