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Molecular basis for N-terminal alpha-synuclein acetylation by human NatB

NatB is one of three major N-terminal acetyltransferase (NAT) complexes (NatA-NatC), which co-translationally acetylate the N-termini of eukaryotic proteins. Its substrates account for about 21% of the human proteome, including well known proteins such as actin, tropomyosin, CDK2, and α-synuclein (α...

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Detalles Bibliográficos
Autores principales: Deng, Sunbin, Pan, Buyan, Gottlieb, Leah, Petersson, E James, Marmorstein, Ronen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494357/
https://www.ncbi.nlm.nih.gov/pubmed/32885784
http://dx.doi.org/10.7554/eLife.57491