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Primary Resistance to Immune Checkpoint Blockade in an STK11/TP53/KRAS-Mutant Lung Adenocarcinoma with High PD-L1 Expression

Several studies have shown that STK11 and TP53 mutations have different effects on the susceptibility to immune checkpoint blockade in KRAS-mutant non-small cell lung cancer (NSCLC). However, the impact of STK11/TP53 co-mutations on treatment outcomes in the same clinical setting has never been repo...

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Detalles Bibliográficos
Autores principales: Kwack, Won Gun, Shin, So Youn, Lee, Seung Hyeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494390/
https://www.ncbi.nlm.nih.gov/pubmed/32982282
http://dx.doi.org/10.2147/OTT.S272013