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T cell receptor signaling defines the fate and pathway of ICOS internalization

The role of the inducible costimulatory of T cells (ICOS) has been shown to be important for many different T cell outcomes and is indispensable for follicular helper T cell (T(FH)) responses. Since its discovery, there have been several studies on the regulation of ICOS at a transcriptional level....

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Detalles Bibliográficos
Autores principales: Lownik, Joseph C., Conrad, Daniel H., Martin, Rebecca K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494666/
https://www.ncbi.nlm.nih.gov/pubmed/32984557
http://dx.doi.org/10.1016/j.bbrep.2020.100803