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Development and Validation of a Novel DNA Methylation-Driven Gene Based Molecular Classification and Predictive Model for Overall Survival and Immunotherapy Response in Patients With Glioblastoma: A Multiomic Analysis

PURPOSE: Glioblastoma (GBM) is the most common primary malignant tumor of the central nervous system, with a 5-year overall survival (OS) rate of only 5.6%. This study aimed to develop a novel DNA methylation-driven gene (MDG)-based molecular classification and risk model for individualized prognosi...

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Detalles Bibliográficos
Autores principales: Wang, Zihao, Gao, Lu, Guo, Xiaopeng, Lian, Wei, Deng, Kan, Xing, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494802/
https://www.ncbi.nlm.nih.gov/pubmed/33015072
http://dx.doi.org/10.3389/fcell.2020.576996