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Redefining the Clostridioides difficile σ(B) Regulon: σ(B) Activates Genes Involved in Detoxifying Radicals That Can Result from the Exposure to Antimicrobials and Hydrogen Peroxide
In many Gram-positive bacteria, the general stress response is regulated at the transcriptional level by the alternative sigma factor sigma B (σ(B)). In C. difficile, σ(B) has been implicated in protection against stressors such as reactive oxygen species (ROS) and antimicrobial compounds. Here, we...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494833/ https://www.ncbi.nlm.nih.gov/pubmed/32938698 http://dx.doi.org/10.1128/mSphere.00728-20 |