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GLN: a method to reveal unique properties of lasso type topology in proteins

Geometry and topology are the main factors that determine the functional properties of proteins. In this work, we show how to use the Gauss linking integral (GLN) in the form of a matrix diagram—for a pair of a loop and a tail—to study both the geometry and topology of proteins with closed loops e.g...

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Detalles Bibliográficos
Autores principales: Niemyska, Wanda, Millett, Kenneth C., Sulkowska, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494857/
https://www.ncbi.nlm.nih.gov/pubmed/32938999
http://dx.doi.org/10.1038/s41598-020-71874-2