Modulation of TRPV-1 by prostaglandin-E(2) and bradykinin changes cough sensitivity and autonomic regulation of cardiac rhythm in healthy subjects

A neurogenic pathway, involving airway TRPV-1, has been implicated in acute cardiovascular events occurring after peaks of air pollution. We tested whether inhaled prostaglandin-E(2) (PGE(2)) and bradykinin (BK) regulate TRPV-1 activity in vivo by changing cough response to capsaicin (CPS) and affec...

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Detalles Bibliográficos
Autores principales: Liviero, Filippo, Scarpa, Maria Cristina, De Stefani, Diego, Folino, Franco, Campisi, Manuela, Mason, Paola, Iliceto, Sabino, Pavanello, Sofia, Maestrelli, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494872/
https://www.ncbi.nlm.nih.gov/pubmed/32938990
http://dx.doi.org/10.1038/s41598-020-72062-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494872/
https://www.ncbi.nlm.nih.gov/pubmed/32938990
http://dx.doi.org/10.1038/s41598-020-72062-y

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