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Modulation of TRPV-1 by prostaglandin-E(2) and bradykinin changes cough sensitivity and autonomic regulation of cardiac rhythm in healthy subjects
A neurogenic pathway, involving airway TRPV-1, has been implicated in acute cardiovascular events occurring after peaks of air pollution. We tested whether inhaled prostaglandin-E(2) (PGE(2)) and bradykinin (BK) regulate TRPV-1 activity in vivo by changing cough response to capsaicin (CPS) and affec...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494872/ https://www.ncbi.nlm.nih.gov/pubmed/32938990 http://dx.doi.org/10.1038/s41598-020-72062-y |