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Viromers as carriers for mRNA-mediated expression of therapeutic molecules under inflammatory conditions

Therapeutic mRNA delivery has been described for several treatment options, such as vaccination and cancer immunotherapy. However, mRNA delivery has to be accompanied by the development and testing of suitable carrier materials due to the instability of mRNAs in human body fluids. In the present stu...

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Detalles Bibliográficos
Autores principales: Jansig, Edith, Geissler, Stefanie, Rieckmann, Vera, Kuenemund, Anja, Hietel, Benjamin, Schenk, Mathias, Wussow, Sebastian, Kreideweiss, Patrick, Panzner, Steffen, Reinsch, Christian, Cynis, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494895/
https://www.ncbi.nlm.nih.gov/pubmed/32934311
http://dx.doi.org/10.1038/s41598-020-72004-8