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Endogenous CCN5 Participates in Angiotensin II/TGF-β(1) Networking of Cardiac Fibrosis in High Angiotensin II-Induced Hypertensive Heart Failure
Aberrant activation of angiotensin II (Ang II) accelerates hypertensive heart failure (HF); this has drawn worldwide attention. The complex Ang II/transforming growth factor (TGF)-β(1) networking consists of central mechanisms underlying pro-fibrotic effects; however, this networking still remains u...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494905/ https://www.ncbi.nlm.nih.gov/pubmed/33013358 http://dx.doi.org/10.3389/fphar.2020.01235 |