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Endogenous CCN5 Participates in Angiotensin II/TGF-β(1) Networking of Cardiac Fibrosis in High Angiotensin II-Induced Hypertensive Heart Failure

Aberrant activation of angiotensin II (Ang II) accelerates hypertensive heart failure (HF); this has drawn worldwide attention. The complex Ang II/transforming growth factor (TGF)-β(1) networking consists of central mechanisms underlying pro-fibrotic effects; however, this networking still remains u...

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Detalles Bibliográficos
Autores principales: Huang, Anan, Li, Huihui, Zeng, Chao, Chen, Wanli, Wei, Liping, Liu, Yue, Qi, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494905/
https://www.ncbi.nlm.nih.gov/pubmed/33013358
http://dx.doi.org/10.3389/fphar.2020.01235

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