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DENR promotes translation reinitiation via ribosome recycling to drive expression of oncogenes including ATF4
Translation efficiency varies considerably between different mRNAs, thereby impacting protein expression. Translation of the stress response master-regulator ATF4 increases upon stress, but the molecular mechanisms are not well understood. We discover here that translation factors DENR, MCTS1 and eI...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494916/ https://www.ncbi.nlm.nih.gov/pubmed/32938922 http://dx.doi.org/10.1038/s41467-020-18452-2 |