Mechanism for the reactivation of the peroxidase activity of human cyclooxygenases: investigation using phenol as a reducing cosubstrate

It has been known for many years that the peroxidase activity of cyclooxygenase 1 and 2 (COX-1 and COX-2) can be reactivated in vitro by the presence of phenol, which serves as a reducing compound, but the underlying mechanism is still poorly understood. In the present study, we use phenol as a mode...

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Detalles Bibliográficos
Autores principales: Yang, Chengxi, Li, Peng, Ding, Xiaoli, Sui, Hao Chen, Rao, Shun, Hsu, Chia-Hsiang, Leung, Wing-Por, Cheng, Gui-Juan, Wang, Pan, Zhu, Bao Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494923/
https://www.ncbi.nlm.nih.gov/pubmed/32938962
http://dx.doi.org/10.1038/s41598-020-71237-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494923/
https://www.ncbi.nlm.nih.gov/pubmed/32938962
http://dx.doi.org/10.1038/s41598-020-71237-x

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