CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells

The identification of the essential role of cyclin-dependent kinases (CDKs) in the control of cell division has prompted the development of small-molecule CDK inhibitors as anticancer drugs. For many of these compounds, the precise mechanism of action in individual tumor types remains unclear as the...

Descripción completa

Detalles Bibliográficos
Autores principales: Štětková, Monika, Growková, Kateřina, Fojtík, Petr, Valčíková, Barbora, Palušová, Veronika, Verlande, Amandine, Jorda, Radek, Kryštof, Vladimír, Hejret, Václav, Alexiou, Panagiotis, Rotrekl, Vladimír, Uldrijan, Stjepan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494941/
https://www.ncbi.nlm.nih.gov/pubmed/32934219
http://dx.doi.org/10.1038/s41419-020-02971-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494941/
https://www.ncbi.nlm.nih.gov/pubmed/32934219
http://dx.doi.org/10.1038/s41419-020-02971-3

Ejemplares similares