HOTAIR Accelerates Dyskinesia in a MPTP-Lesioned Mouse Model of PD via SSTR1 Methylation-Mediated ERK1/2 Axis

Homeobox transcript antisense RNA (HOTAIR), has been associated with neuroprotective effects in Parkinson’s disease (PD). However, the underlying mechanisms still remain unclear. Hence, this present study attempted to clarify the functional relevance of HOTAIR in PD. We established an in vivo mouse...

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Detalles Bibliográficos
Autores principales: Cai, Lijun, Tu, Li, Yang, Xiulin, Zhang, Qian, Tian, Tian, Gu, Rang, Qu, Xiang, Wang, Qian, Tian, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494946/
https://www.ncbi.nlm.nih.gov/pubmed/32927363
http://dx.doi.org/10.1016/j.omtn.2020.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494946/
https://www.ncbi.nlm.nih.gov/pubmed/32927363
http://dx.doi.org/10.1016/j.omtn.2020.07.019

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