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Promiscuous DNA cleavage by HpyAII endonuclease is modulated by the HNH catalytic residues

Helicobacter pylori is a carcinogenic bacterium that is responsible for 5.5% of all human gastric cancers. H. pylori codes for an unusually large number of restriction–modification (R–M) systems and several of them are strain-specific and phase-variable. HpyAII is a novel Type IIs phase-variable res...

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Detalles Bibliográficos
Autores principales: Kumar, Sumith, Bangru, Sushant, Kumar, Ritesh, Rao, Desirazu N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494987/
https://www.ncbi.nlm.nih.gov/pubmed/32880391
http://dx.doi.org/10.1042/BSR20201633