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Acute toxicity analysis of Disarib, an inhibitor of BCL2

Small molecule inhibitors targeting BCL2 are explored as anticancer therapeutics. Previously, we have reported identification and characterization of a novel BCL2 inhibitor, Disarib. Disarib induced cancer cell death in a BCL2 dependent manner in different cancer cell lines and mouse tumor models wh...

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Detalles Bibliográficos
Autores principales: Sharma, Shivangi, Varsha, Kontham Kulangara, Kumari, Susmita, Gopalakrishnan, Vidya, Jose, Anjana Elizabeth, Choudhary, Bibha, Mantelingu, Kempegowda, Raghavan, Sathees C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7494999/
https://www.ncbi.nlm.nih.gov/pubmed/32938954
http://dx.doi.org/10.1038/s41598-020-72058-8