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Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy

Innate lymphoid cells (ILCs) are important for response to infection and for immune development in early life. HIV infection in adults depletes circulating ILCs, but the impact on children infected from birth remains unknown. We study vertically HIV-infected children from birth to adulthood and find...

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Detalles Bibliográficos
Autores principales: Singh, Alveera, Kazer, Samuel W., Roider, Julia, Krista, Kami C., Millar, Jane, Asowata, Osaretin E., Ngoepe, Abigail, Ramsuran, Duran, Fardoos, Rabiah, Ardain, Amanda, Muenchhoff, Maximilian, Kuhn, Warren, Karim, Farina, Ndung’u, Thumbi, Shalek, Alex K., Goulder, Philip, Leslie, Alasdair, Kløverpris, Henrik N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495043/
https://www.ncbi.nlm.nih.gov/pubmed/32937142
http://dx.doi.org/10.1016/j.celrep.2020.108153