Protein Stability Buffers the Cost of Translation Attenuation following eIF2α Phosphorylation

Phosphorylation of the translation initiation factor eIF2α is a rapid and vital response to many forms of stress, including protein-misfolding stress in the endoplasmic reticulum (ER stress). It is believed to cause a general reduction in protein synthesis while enabling translation of few transcrip...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider, Kim, Nelson, Geoffrey Michael, Watson, Joseph Luke, Morf, Jörg, Dalglish, Maximillian, Luh, Laura Martina, Weber, Annika, Bertolotti, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495045/
https://www.ncbi.nlm.nih.gov/pubmed/32937139
http://dx.doi.org/10.1016/j.celrep.2020.108154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7495045/
https://www.ncbi.nlm.nih.gov/pubmed/32937139
http://dx.doi.org/10.1016/j.celrep.2020.108154

Ejemplares similares